ARO-Studien: Publikationen (Stand 28.12.2022)
Analkarzinom
- Grabenbauer GG, Panzer M, Hultenschmidt B, Doker R, Huber K, Kuhne-Velte HJ, Hutter M, Ruhl U, Budach V, Wendt T et al: [The prognostic factors following the simultaneous radiochemotherapy of anal canal carcinoma in a multicenter series of 139 patients]. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al] 1994, 170(7):391-399.
- Martin D, Balermpas P, Gollrad J, Weiss C, Valentini C, Stuschke M, Schafer H, Henckenberens C, Debus J, Krug D et al: RADIANCE - Radiochemotherapy with or without Durvalumab in the treatment of anal squamous cell carcinoma: A randomized multicenter phase II trial. Clin Transl Radiat Oncol 2020, 23:43-49.
Hirntumore
- Oehlke O, Mix M, Graf E, Schimek-Jasch T, Nestle U, Gotz I, Schneider-Fuchs S, Weyerbrock A, Mader I, Baumert BG et al: Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - protocol of a randomized phase II trial (NOA 10/ARO 2013-1). BMC cancer 2016, 16(1):769.
- Straube C, Scherb H, Gempt J, Kirschke J, Zimmer C, Schmidt-Graf F, Meyer B, Combs SE: Adjuvant stereotactic fractionated radiotherapy to the resection cavity in recurrent glioblastoma - the GlioCave study (NOA 17 - ARO 2016/3 - DKTK ROG trial). BMC cancer 2018, 18(1):15.
Hodentumore
- Gobel U, Bamberg M, Calaminus G, Jurgens H, Pelzer V, Simon WE, Terruhn V, Wolf A, Mecke H, Harms D: [Dysgerminomas. Clinical aspects, therapy and prognosis with reference to the cooperative therapy study MAIKEI 83/86 for non-testicular germ cell tumors of the Society of Pediatric Oncology]. Geburtshilfe Frauenheilkd 1989, 49(8):737-742.
- Gobel U, Bamberg M, Haas RJ, Bokkerink JP, Bramswig G, Calaminus G, Engert J, Gadner H, Havers W, Janka-Schaub GE et al: [Non-testicular germ cell tumors: analysis of the therapy study MAKEI 83/86 anc changes in the protocol for the follow-up study]. Klin Padiatr 1989, 201(4):247-260.
- Gobel U, Bamberg M, Engert J, Gnekow AK, Haas HJ, Jurgens H, Kuhl J, Lenard HG, Lumenta C, Niethammer D et al: [Treatment of non-testicular germ cell tumors in children and adolescents with BEP and VIP: initial results of the MAKEI 89 therapy study]. Klin Padiatr 1991, 203(4):236-245.
- Gobel U, Calaminus G, Teske C, Bamberg M, Bokkerink JP, Haas RJ, Holschneider AM, Janka-Schaub G, Jurgens H, Mittler U et al: [BEP/VIP in children and adolescents with malignant non-testicular germ cell tumors. A comparison of the results of treatment of therapy studies MAKEI 83/86 and 89P/89]. Klin Padiatr 1993, 205(4):231-240.
- Schmidberger H, Bamberg M: [Treatment options in early-stage testicular seminoma. Review of the literature with initial results of a prospective multicenter study on radiotherapy of clinical-stage I, IIA and IIB seminomas]. Strahlenther Onkol 1995, 171(3):125-139.
- Schmidberger H, Bamberg M, Meisner C, Classen J, Winkler C, Hartmann M, Templin R, Wiegel T, Dornoff W, Ross D et al: Radiotherapy in stage IIA and IIB testicular seminoma with reduced portals: a prospective multicenter study. Int J Radiat Oncol Biol Phys 1997, 39(2):321-326.
- Bamberg M, Schmidberger H, Meisner C, Classen J, Souchon R, Weinknecht S, Schorcht J, Walter F, Engenhart-Cabillic R, Schulz U et al: Radiotherapy for stages I and IIA/B testicular seminoma. Int J Cancer 1999, 83(6):823-827.
- Classen J, Souchon R, Hehr T, Bamberg M: Radiotherapy for early stages testicular seminoma: patterns of care study in Germany. Radiother Oncol 2002, 63(2):179-186.
- Classen J, Dieckmann K, Bamberg M, Souchon R, Kliesch S, Kuehn M, Loy V, German Testicular Cancer Study G: Radiotherapy with 16 Gy may fail to eradicate testicular intraepithelial neoplasia: preliminary communication of a dose-reduction trial of the German Testicular Cancer Study Group. Br J Cancer 2003, 88(6):828-831.
- Classen J, Schmidberger H, Meisner C, Souchon R, Sautter-Bihl ML, Sauer R, Weinknecht S, Kohrmann KU, Bamberg M: Radiotherapy for stages IIA/B testicular seminoma: final report of a prospective multicenter clinical trial. J Clin Oncol 2003, 21(6):1101-1106.
- Classen J, Schmidberger H, Meisner C, Winkler C, Dunst J, Souchon R, Weissbach L, Budach V, Alberti W, Bamberg M et al: Para-aortic irradiation for stage I testicular seminoma: results of a prospective study in 675 patients. A trial of the German testicular cancer study group (GTCSG). Br J Cancer 2004, 90(12):2305-2311.
- Clasen J, Schmidberger H, Souchon R, Weissbach L, Hartmann M, Hartmann JT, Hehr T, Bamberg M: What is the value of routine follow-up in stage I seminoma after paraaortic radiotherapy?: an analysis of the German Testicular Cancer Study Group (GTCSG) in 675 prospectively followed patients. Strahlenther Onkol 2009, 185(6):349-354.
Kopf-Hals-Tumore
- Volling P, Staar S, Achterrath W, Muller RP: Phase I/II study of simultaneous carboplatin and radiotherapy in unresectable squamous cell carcinoma of the head and neck. Seminars in oncology 1992, 19(1 Suppl 2):66-71.
- Dinges S, Budach V, Stuschke M, Budach W, Boehmer D, Schrader M, Jahnke K, Sack H: Chemo-radiotherapy for locally advanced head and neck cancer--long-term results of a phase II trial. European journal of cancer 1997, 33(7):1152-1155.
- Hoffmann W, Belka C, Schmidberger H, Budach W, Bochtler H, Hess CF, Bamberg M: Radiotherapy and concomitant weekly 1-hour infusion of paclitaxel in the treatment of head and neck cancer--results from a Phase I trial. International journal of radiation oncology, biology, physics 1997, 38(4):691-696.
- Wendt TG, Grabenbauer GG, Rodel CM, Thiel HJ, Aydin H, Rohloff R, Wustrow TP, Iro H, Popella C, Schalhorn A: Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: a randomized multicenter study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998, 16(4):1318-1324.
- Brizel DM, Wasserman TH, Henke M, Strnad V, Rudat V, Monnier A, Eschwege F, Zhang J, Russell L, Oster W et al: Phase III randomized trial of amifostine as a radioprotector in head and neck cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000, 18(19):3339-3345.
- Staar S, Rudat V, Stuetzer H, Dietz A, Volling P, Schroeder M, Flentje M, Eckel HE, Mueller RP: Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy--results of a multicentric randomized German trial in advanced head-and-neck cancer. International journal of radiation oncology, biology, physics 2001, 50(5):1161-1171.
- Henke M, Laszig R, Rube C, Schafer U, Haase KD, Schilcher B, Mose S, Beer KT, Burger U, Dougherty C et al: Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 2003, 362(9392):1255-1260.
- Ernst-Stecken A, Grabenbauer G, Iro H, Plasswilm L, Sauer R: Phase II trial of hyperfractionated accelerated split-course radiochemotherapy with 5-FU and Cis-DDP in advanced head and neck cancer: results and toxicity. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft [et al] 2004, 180(12):805-810.
- Budach V, Stuschke M, Budach W, Baumann M, Geismar D, Grabenbauer G, Lammert I, Jahnke K, Stueben G, Herrmann T et al: Hyperfractionated accelerated chemoradiation with concurrent fluorouracil-mitomycin is more effective than dose-escalated hyperfractionated accelerated radiation therapy alone in locally advanced head and neck cancer: final results of the radiotherapy cooperative clinical trials group of the German Cancer Society 95-06 Prospective Randomized Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005, 23(6):1125-1135.
- Hehr T, Classen J, Belka C, Welz S, Schafer J, Koitschev A, Bamberg M, Budach W: Reirradiation alternating with docetaxel and cisplatin in inoperable recurrence of head-and-neck cancer: a prospective phase I/II trial. International journal of radiation oncology, biology, physics 2005, 61(5):1423-1431.
- Wasserman TH, Brizel DM, Henke M, Monnier A, Eschwege F, Sauer R, Strnad V: Influence of intravenous amifostine on xerostomia, tumor control, and survival after radiotherapy for head-and- neck cancer: 2-year follow-up of a prospective, randomized, phase III trial. International journal of radiation oncology, biology, physics 2005, 63(4):985-990.
- Kuhnt T, Becker A, Bloching M, Schubert J, Klautke G, Fietkau R, Dunst J: Phase II trial of a simultaneous radiochemotherapy with cisplatinum and paclitaxel in combination with hyperfractionated-accelerated radiotherapy in locally advanced head and neck tumors. Medical oncology 2006, 23(3):325-333.
- Semrau R, Mueller RP, Stuetzer H, Staar S, Schroeder U, Guntinas-Lichius O, Kocher M, Eich HT, Dietz A, Flentje M et al: Efficacy of intensified hyperfractionated and accelerated radiotherapy and concurrent chemotherapy with carboplatin and 5-fluorouracil: updated results of a randomized multicentric trial in advanced head-and-neck cancer. International journal of radiation oncology, biology, physics 2006, 64(5):1308-1316.
- Kuhnt T, Sandner A, Wendt T, Engenhart-Cabillic R, Lammering G, Flentje M, Grabenbauer G, Schreiber A, Pirnasch A, Dunst J: Phase I trial of dose-escalated cisplatin with concomitant cetuximab and hyperfractionated-accelerated radiotherapy in locally advanced squamous cell carcinoma of the head and neck. Annals of oncology : official journal of the European Society for Medical Oncology 2010, 21(11):2284-2289.
- Henke M, Alfonsi M, Foa P, Giralt J, Bardet E, Cerezo L, Salzwimmer M, Lizambri R, Emmerson L, Chen MG et al: Palifermin decreases severe oral mucositis of patients undergoing postoperative radiochemotherapy for head and neck cancer: a randomized, placebo-controlled trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011, 29(20):2815-2820.
- Zips D, Zophel K, Abolmaali N, Perrin R, Abramyuk A, Haase R, Appold S, Steinbach J, Kotzerke J, Baumann M: Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2012, 105(1):21-28.
- Budach V, Becker ET, Boehmer D, Badakhshi H, Jahn U, Wernecke KD, Stromberger C: Concurrent hyperfractionated accelerated radiotherapy with 5-FU and once weekly cisplatin in locally advanced head and neck cancer. The 10-year results of a prospective phase II trial. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft [et al] 2014, 190(3):250-255.
- Budach V, Stromberger C, Poettgen C, Baumann M, Budach W, Grabenbauer G, Marnitz S, Olze H, Wernecke KD, Ghadjar P: Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial. International journal of radiation oncology, biology, physics 2015, 91(5):916-924.
- Ghadjar P, Pottgen C, Joos D, Hayoz S, Baumann M, Bodis S, Budach W, Studer G, Stromberger C, Zimmermann F et al: Haemoglobin and creatinine values as prognostic factors for outcome of concurrent radiochemotherapy in locally advanced head and neck cancers : Secondary results of two European randomized phase III trials (ARO 95-06, SAKK 10/94). Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft [et al] 2016, 192(8):552-560.
- Tinhofer I, Budach V, Saki M, Konschak R, Niehr F, Johrens K, Weichert W, Linge A, Lohaus F, Krause M et al: Targeted next-generation sequencing of locally advanced squamous cell carcinomas of the head and neck reveals druggable targets for improving adjuvant chemoradiation. European journal of cancer 2016, 57:78-86.
- Hess AK, Muer A, Mairinger FD, Weichert W, Stenzinger A, Hummel M, Budach V, Tinhofer I: MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma. European journal of cancer 2017, 77:3-12.
- Hess AK, Johrens K, Zakarneh A, Balermpas P, Von Der Grun J, Rodel C, Weichert W, Hummel M, Keilholz U, Budach V et al: Characterization of the tumor immune micromilieu and its interference with outcome after concurrent chemoradiation in patients with oropharyngeal carcinomas. Oncoimmunology 2019, 8(8):1614858.
- Pigorsch SU, Kampfer S, Oechsner M, Mayinger MC, Mozes P, Devecka M, Kessel KK, Combs SE, Wilkens JJ: Report on planning comparison of VMAT, IMRT and helical tomotherapy for the ESCALOX-trial pre-study. Radiat Oncol 2020, 15(1):253.
- Fietkau R, Hecht M, Hofner B, Lubgan D, Iro H, Gefeller O, Rodel C, Hautmann MG, Kolbl O, Salay A et al: Randomized phase-III-trial of concurrent chemoradiation for locally advanced head and neck cancer comparing dose reduced radiotherapy with paclitaxel/cisplatin to standard radiotherapy with fluorouracil/cisplatin: The PacCis-trial. Radiother Oncol 2020, 144:209-217.
Lebensqualität und PRO
- Hauth F, Gehler B, Niess AM, Fischer K, Toepell A, Heinrich V, Roesel I, Peter A, Renovanz M, Hartkopf A et al: An Activity Tracker-Guided Physical Activity Program for Patients Undergoing Radiotherapy: Protocol for a Prospective Phase III Trial (OnkoFit I and II Trials). JMIR Res Protoc 2021, 10(9):e28524.
- Fabian A, Domschikowski J, Letsch A, Schmalz C, Freitag-Wolf S, Dunst J, Krug D: Clinical endpoints in trials of palliative radiotherapy: A systematic meta-research analysis. Radiother Oncol 2022, 174:123-131.
- Fabian A, Domschikowski J, Letsch A, Schmalz C, Freitag-Wolf S, Dunst J, Krug D: Use and Reporting of Patient-Reported Outcomes in Trials of Palliative Radiotherapy: A Systematic Review. JAMA Netw Open 2022, 5(9):e2231930.
Lungenkarzinom
- Fleckenstein J, Hellwig D, Kremp S, Grgic A, Groschel A, Kirsch CM, Nestle U, Rube C: F-18-FDG-PET confined radiotherapy of locally advanced NSCLC with concomitant chemotherapy: results of the PET-PLAN pilot trial. International journal of radiation oncology, biology, physics 2011, 81(4):e283-289.
- Baumann M, Herrmann T, Koch R, Matthiessen W, Appold S, Wahlers B, Kepka L, Marschke G, Feltl D, Fietkau R et al: Final results of the randomized phase III CHARTWEL-trial (ARO 97-1) comparing hyperfractionated-accelerated versus conventionally fractionated radiotherapy in non-small cell lung cancer (NSCLC). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2011, 100(1):76-85.
- Soliman M, Yaromina A, Appold S, Zips D, Reiffenstuhl C, Schreiber A, Thames HD, Krause M, Baumann M: GTV differentially impacts locoregional control of non-small cell lung cancer (NSCLC) after different fractionation schedules: subgroup analysis of the prospective randomized CHARTWEL trial. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2013, 106(3):299-304.
- Eberhardt WE, Pottgen C, Gauler TC, Friedel G, Veit S, Heinrich V, Welter S, Budach W, Spengler W, Kimmich M et al: Phase III Study of Surgery Versus Definitive Concurrent Chemoradiotherapy Boost in Patients With Resectable Stage IIIA(N2) and Selected IIIB Non-Small-Cell Lung Cancer After Induction Chemotherapy and Concurrent Chemoradiotherapy (ESPATUE). Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2015, 33(35):4194-4201.
- Pottgen C, Gauler T, Bellendorf A, Guberina M, Bockisch A, Schwenzer N, Heinzelmann F, Cordes S, Schuler MH, Welter S et al: Standardized Uptake Decrease on [18F]-Fluorodeoxyglucose Positron Emission Tomography After Neoadjuvant Chemotherapy Is a Prognostic Classifier for Long-Term Outcome After Multimodality Treatment: Secondary Analysis of a Randomized Trial for Resectable Stage IIIA/B Non-Small-Cell Lung Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2016, 34(21):2526-2533.
- Butof R, Simon M, Lock S, Troost EGC, Appold S, Krause M, Baumann M: PORTAF - postoperative radiotherapy of non-small cell lung cancer: accelerated versus conventional fractionation - study protocol for a randomized controlled trial. Trials 2017, 18(1):608.
- Hechtner M, Krause M, Konig J, Appold S, Hornemann B, Singer S, Baumann M: Long-term quality of life in inoperable non-small cell lung cancer patients treated with conventionally fractionated compared to hyperfractionated accelerated radiotherapy - Results of the randomized CHARTWEL trial. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018, 126(2):283-290.
- Guberina M, Eberhardt W, Stuschke M, Gauler T, Aigner C, Schuler M, Stamatis G, Theegarten D, Jentzen W, Herrmann K et al: Pretreatment metabolic tumour volume in stage IIIA/B non-small-cell lung cancer uncovers differences in effectiveness of definitive radiochemotherapy schedules: analysis of the ESPATUE randomized phase 3 trial. European journal of nuclear medicine and molecular imaging 2019, 46(7):1439-1447.
- Nestle U, Schimek-Jasch T, Kremp S, Schaefer-Schuler A, Mix M, Kusters A, Tosch M, Hehr T, Eschmann SM, Bultel YP et al: Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial. Lancet Oncol 2020, 21(4):581-592.
- Gkika E, Lenz S, Schimek-Jasch T, Waller CF, Kremp S, Schaefer-Schuler A, Mix M, Kusters A, Tosch M, Hehr T et al: Efficacy and Toxicity of Different Chemotherapy Protocols for Concurrent Chemoradiation in Non-Small Cell Lung Cancer-A Secondary Analysis of the PET Plan Trial. Cancers (Basel) 2020, 12(11).
- Gkika E, Schimek-Jasch T, Kremp S, Lenz S, Stockinger M, Schaefer-Schuler A, Mix M, Kusters A, Tosch M, Hehr T et al: Impact of radiotherapy protocol adherence in NSCLC patients treated with concurrent chemoradiation: RTQA results of the PET-Plan trial. Radiother Oncol 2021, 163:32-38.
- Carles M, Fechter T, Radicioni G, Schimek-Jasch T, Adebahr S, Zamboglou C, Nicolay NH, Marti-Bonmati L, Nestle U, Grosu AL et al: FDG-PET Radiomics for Response Monitoring in Non-Small-Cell Lung Cancer Treated with Radiation Therapy. Cancers (Basel) 2021, 13(4).
- Regnery S, Ristau J, Weykamp F, Hoegen P, Sprengel SD, Paul KM, Buchele C, Kluter S, Rippke C, Renkamp CK et al: Magnetic resonance guided adaptive stereotactic body radiotherapy for lung tumors in ultracentral location: the MAGELLAN trial (ARO 2021-3). Radiat Oncol 2022, 17(1):102.
- Maurer M, Kasmann L, Fleischmann DF, Oertel M, Jazmati D, Medenwald D, Young DTG: PET/CT-based adaptive radiotherapy of locally advanced non-small cell lung cancer in multicenter yDEGRO ARO 2017-01 cohort study. Radiat Oncol 2022, 17(1):29.
- Kasmann L, Taugner J, Eze C, Nieto A, Pelikan C, Florsch B, Kenndoff S, Hofer TP, Nossner E, Schulz C et al: Prospective evaluation of immunological, molecular-genetic, image-based and microbial analyses to characterize tumor response and control in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy followed by consolidation therapy with durvalumab (PRECISION): protocol for a prospective longitudinal biomarker study. Transl Lung Cancer Res 2022, 11(7):1503-1509.
Mammakarzinom
- Winzer KJ, Sauerbrei W, Braun M, Liersch T, Dunst J, Guski H, Schumacher M, German Breast Cancer Study G: Radiation therapy and tamoxifen after breast-conserving surgery: updated results of a 2 x 2 randomised clinical trial in patients with low risk of recurrence. European journal of cancer 2010, 46(1):95-101.
- Dellas K, Vonthein R, Zimmer J, Dinges S, Boicev AD, Andreas P, Fischer D, Winkler C, Ziegler A, Dunst J et al: Hypofractionation with simultaneous integrated boost for early breast cancer: results of the German multicenter phase II trial (ARO-2010-01). Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al] 2014, 190(7):646-653.
- Krug D, Baumann R, Krockenberger K, Vonthein R, Schreiber A, Boicev A, Wurschmidt F, Weinstrauch E, Eilf K, Andreas P et al: Adjuvant hypofractionated radiotherapy with simultaneous integrated boost after breast-conserving surgery: results of a prospective trial. Strahlenther Onkol 2021, 197(1):48-55.
- Krug D, Vonthein R, Illen A, Olbrich D, Barkhausen J, Richter J, Klapper W, Schmalz C, Rody A, Maass N et al: Metastases-directed Radiotherapy in Addition to Standard Systemic Therapy in Patients with Oligometastatic Breast Cancer: Study protocol for a randomized controlled multi-national and multi-center clinical trial (OLIGOMA). Clin Transl Radiat Oncol 2021, 28:90-96.
- Pfaffendorf C, Vonthein R, Krockenberger-Ziegler K, Dellas K, Schreiber A, Uhlemann D, Dinges S, Wurschmidt F, Andreas P, Weinstrauch E et al: Hypofractionation with simultaneous integrated boost after breast-conserving surgery: Long term results of two phase-II trials. Breast 2022, 64:136-142.
Metastasen
- Wiegel T, Bottke D, Kreusel KM, Schmidt S, Bornfeld N, Foerster MH, Hinkelbein W, German Cancer S: External beam radiotherapy of choroidal metastases--final results of a prospective study of the German Cancer Society (ARO 95-08). Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2002, 64(1):13-18.
- Rades D, Segedin B, Conde-Moreno AJ, Garcia R, Perpar A, Metz M, Badakhshi H, Schreiber A, Nitsche M, Hipp P et al: Radiotherapy With 4 Gy x 5 Versus 3 Gy x 10 for Metastatic Epidural Spinal Cord Compression: Final Results of the SCORE-2 Trial (ARO 2009/01). Journal of clinical oncology: official journal of the American Society of Clinical Oncology 2016, 34(6):597-602.
- Grosu AL, Frings L, Bentsalo I, Oehlke O, Brenner F, Bilger A, Fennell JT, Rothe T, Schneider-Fuchs S, Graf E et al: Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) - a phase II prospective randomized multicenter trial (NOA-14, ARO 2015-3, DKTK-ROG). BMC Cancer 2020, 20(1):532.
- Popp I, Rau A, Kellner E, Reisert M, Fennell JT, Rothe T, Nieder C, Urbach H, Egger K, Grosu AL et al: Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume. Front Oncol 2021, 11:714709.
Pankreaskarzinom
- Brunner TB, Grabenbauer GG, Klein P, Baum U, Papadopoulos T, Bautz W, Hohenberger W, Sauer R: Phase I trial of strictly time-scheduled gemcitabine and cisplatin with concurrent radiotherapy in patients with locally advanced pancreatic cancer. International journal of radiation oncology, biology, physics 2003, 55(1):144-153.
- Brunner TB, Geiger M, Grabenbauer GG, Lang-Welzenbach M, Mantoni TS, Cavallaro A, Sauer R, Hohenberger W, McKenna WG: Phase I trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology 2008, 26(16):2699-2706.
- Golcher H, Brunner TB, Witzigmann H, Marti L, Bechstein WO, Bruns C, Jungnickel H, Schreiber S, Grabenbauer GG, Meyer T et al: Neoadjuvant chemoradiation therapy with gemcitabine/cisplatin and surgery versus immediate surgery in resectable pancreatic cancer: results of the first prospective randomized phase II trial. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al] 2015, 191(1):7-16.
- Wittel UA, Lubgan D, Ghadimi M, Belyaev O, Uhl W, Bechstein WO, Grutzmann R, Hohenberger WM, Schmid A, Jacobasch L et al: Consensus in determining the resectability of locally progressed pancreatic ductal adenocarcinoma - results of the Conko-007 multicenter trial. BMC Cancer 2019, 19(1):979.
- Fietkau R, Grutzmann R, Wittel UA, Croner RS, Jacobasch L, Neumann UP, Reinacher-Schick A, Imhoff D, Boeck S, Keilholz L et al: R0 resection following chemo (radio)therapy improves survival of primary inoperable pancreatic cancer patients. Interim results of the German randomized CONKO-007+/- trial. Strahlenther Onkol 2021, 197(1):8-18.
- Pavic M, Niyazi M, Wilke L, Corradini S, Vornhulz M, Mansmann U, Al Tawil A, Fritsch R, Horner-Rieber J, Debus J et al: MR-guided adaptive stereotactic body radiotherapy (SBRT) of primary tumor for pain control in metastatic pancreatic ductal adenocarcinoma (mPDAC): an open randomized, multicentric, parallel group clinical trial (MASPAC). Radiat Oncol 2022, 17(1):18.
Prostatakarzinom
- Wiegel T, Bottke D, Steiner U, Siegmann A, Golz R, Storkel S, Willich N, Semjonow A, Souchon R, Stockle M et al: Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009, 27(18):2924-2930.
- Bottke D, Golz R, Storkel S, Hinke A, Siegmann A, Hertle L, Miller K, Hinkelbein W, Wiegel T: Phase 3 study of adjuvant radiotherapy versus wait and see in pT3 prostate cancer: impact of pathology review on analysis. European urology 2013, 64(2):193-198.
- Wiegel T, Bartkowiak D, Bottke D, Bronner C, Steiner U, Siegmann A, Golz R, Storkel S, Willich N, Semjonow A et al: Adjuvant radiotherapy versus wait-and-see after radical prostatectomy: 10-year follow-up of the ARO 96-02/AUO AP 09/95 trial. European urology 2014, 66(2):243-250.
- Wiegel T, Bartkowiak D, Bottke D, Thamm R, Hinke A, Stockle M, Rube C, Semjonow A, Wirth M, Storkel S et al: Prostate-specific antigen persistence after radical prostatectomy as a predictive factor of clinical relapse-free survival and overall survival: 10-year data of the ARO 96-02 trial. International journal of radiation oncology, biology, physics 2015, 91(2):288-294.
- Habl G, Katayama S, Uhl M, Kessel KA, Edler L, Debus J, Herfarth K, Sterzing F: Helical intensity-modulated radiotherapy of the pelvic lymph nodes with a simultaneous integrated boost to the prostate--first results of the PLATIN 1 trial. BMC cancer 2015, 15:868.
- Jiang P, Krockenberger K, Vonthein R, Tereszczuk J, Schreiber A, Liebau S, Huttenlocher S, Imhoff D, Balermpas P, Keller C et al: Hypo-fractionated SBRT for localized prostate cancer: a German bi-center single treatment group feasibility trial. Radiation oncology 2017, 12(1):138.
- Ghadjar P, Aebersold DM, Albrecht C, Bohmer D, Flentje M, Ganswindt U, Hocht S, Holscher T, Muller AC, Niehoff P et al: Treatment strategies to prevent and reduce gynecomastia and/or breast pain caused by antiandrogen therapy for prostate cancer: Statement from the DEGRO working group prostate cancer. Strahlenther Onkol 2020, 196(7):589-597.
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